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De novo human genome assemblies reveal spectrum of alternative haplotypes in diverse populations
The human reference genome is used extensively in modern biological research. However, a single consensus representation is inadequate to provide a universal reference structure because it is a haplotype among many in the human population. Using 10× Genomics (10×G) “Linked-Read” technology, we perfo...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072799/ https://ncbi.nlm.nih.gov/pubmed/30072691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05513-w |
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