EPIGENETIC TARGETING OF ADIPOCYTES INHIBITS HIGH-GRADE SEROUS OVARIAN CANCER CELL MIGRATION AND INVASION

Ovarian cancer (OC) cells frequently metastasize to the omentum and adipocytes play a significant role in ovarian tumor progression. Therapeutic interventions targeting aberrant DNA methylation in ovarian tumors have shown promise in the clinic but the effects of epigenetic therapy on the tumor micr...

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Publicat a:Mol Cancer Res
Autors principals: Tang, Jessica, Pulliam, Nicholas, Özeş, Ali, Buechlein, Aaron, Ding, Ning, Keer, Harold, Rusch, Doug, O’Hagan, Heather, Stack, M. Sharon, Nephew, Kenneth P.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072573/
https://ncbi.nlm.nih.gov/pubmed/29759990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-17-0406
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