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Genomic-Epidemiologic Evidence that Estrogens Promote Breast Cancer Development

BACKGROUND: Estrogens are a prime risk factor for breast cancer yet their causal relation to tumor formation remains uncertain. A recent study of 560 breast cancers identified 82 genes with 916 point mutations as drivers in the genesis of this malignancy. Since estrogens play a major role in breast...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Epidemiol Biomarkers Prev
Hauptverfasser: Parl, Fritz F., Crooke, Philip S., Plummer, W. Dale, Dupont, William D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072561/
https://ncbi.nlm.nih.gov/pubmed/29789325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-17-1174
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