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Synthesis of novel inhibitors of α-amylase based on the thiazolidine-4-one skeleton containing a pyrazole moiety and their configurational studies

Postprandial hyperglycemia can be controlled by delaying the absorption of glucose resulting from carbohydrate digestion. α-Amylase is the initiator of the hydrolysis of polysaccharides, and therefore developing α-amylase inhibitors can lead to development of new treatments for metabolic disorders l...

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Vydáno v:Medchemcomm
Hlavní autoři: Kumar, Parvin, Duhan, Meenakshi, Kadyan, Kulbir, Sindhu, Jayant, Kumar, Sunil, Sharma, Hitender
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072529/
https://ncbi.nlm.nih.gov/pubmed/30108858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00080d
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