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Design, synthesis and cytotoxicity of bengamide analogues and their epimers

Starting from d-glycero-d-gulo-heptonic acid γ-lactone and amino acids, a number of diastereoisomeric bengamide analogues were synthesized. Optimization of the reaction conditions revealed that microwave irradiation assistance is a powerful method for the preparation of aminolactams, as well as for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Medchemcomm
Hauptverfasser: Phi, Thi Dao, Doan Thi Mai, Huong, Tran, Van Hieu, Truong, Bich Ngan, Tran, Tuan Anh, Vu, Van Loi, Chau, Van Minh, Pham, Van Cuong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072509/
https://ncbi.nlm.nih.gov/pubmed/30108762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00587j
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