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5,6-Benzoflavones as cholesterol esterase inhibitors: synthesis, biological evaluation and docking studies

In a continued effort to develop potent cholesterol esterase (CEase) inhibitors, a series of 5,6-benzoflavone derivatives was rationally designed and synthesized by changing the position of the benzene ring attached to the flavone skeleton in previously reported 7,8-benzoflavones. All the synthesize...

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Publicat a:Medchemcomm
Autors principals: Singh, Jatinder V., Kaur, Anumeet, Bhagat, Kavita, Gupta, Manish K., Singh, Manwinder, Singh, Harbinder, Bedi, Preet Mohinder S.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072486/
https://ncbi.nlm.nih.gov/pubmed/30108939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00565b
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