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Synthesis, crystal structure, cytotoxicity and action mechanism of a Rh(iii) complex with 8-hydroxy-2-methylquinoline as a ligand
A rhodium(iii) complex, [Rh(MQ)(DMSO)(2)Cl(2)] (1), with 8-hydroxy-2-methylquinoline as the ligand was synthesized and characterized. Complex 1 exhibited cytotoxicity against BEL-7404, Hep-G2, NCI-H460, T-24, and A549 cell lines with IC(50) values in the micromolar range (6.52–17.86 μM). Various exp...
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| Publicado no: | Medchemcomm |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072358/ https://ncbi.nlm.nih.gov/pubmed/30108704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00462h |
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