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Synthesis, α-glucosidase inhibition and molecular docking studies of novel thiazolidine-2,4-dione or rhodanine derivatives
A series of novel thiazolidine-2,4-dione or rhodanine derivatives (5a–5k, 6a–6k) were synthesized and evaluated for their α-glucosidase inhibitory activity. The majority of compounds exhibited potent inhibitory activity in the range of 5.44 ± 0.13 to 50.45 ± 0.39 μM, when compared to the standard dr...
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| Publicat a: | Medchemcomm |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Royal Society of Chemistry
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072357/ https://ncbi.nlm.nih.gov/pubmed/30108859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00173h |
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