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Remarkably Efficient Blood–Brain Barrier Crossing Polyfluorene–Chitosan Nanoparticle Selectively Tweaks Amyloid Oligomer in Cerebrospinal Fluid and Aβ1–40

[Image: see text] Amyloid oligomers have emerged as a key neurotoxin in Alzheimer’s dementia. Amyloid aggregation inhibitors and modulators have therefore offered potential applications in therapeutics and diagnosis. However, crossing the blood–brain barrier (BBB) and finding the toxic aggregates am...

詳細記述

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書誌詳細
出版年:ACS Omega
主要な著者: Roy Chowdhury, Sayan, Mondal, Subrata, Muthuraj, Balakrishnan, Balaji, S. N., Trivedi, Vishal, Krishnan Iyer, Parameswar
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2018
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072248/
https://ncbi.nlm.nih.gov/pubmed/30087934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b00764
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