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A histone H1-binding-aptide-based apoptosis imaging probe for monitoring tumor responses to cancer therapy

Here we report the feasibility of using a high-affinity histone H1-binding peptide as a potential molecular apoptosis imaging probe. The Cy5.5-labeled peptide showed high selectivity for drug-treated apoptotic tumors compared with non-apoptotic tumors in various in vivo settings, enabling detection...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Lee, Yonghyun, Kim, Sunghyun, Kim, Daejin, Jon, Sangyong
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071975/
https://ncbi.nlm.nih.gov/pubmed/30108755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00696e
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