Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries

Women and other mammalian females are born with a finite supply of oocytes that determine their reproductive lifespan. During fetal development, individual oocytes are enclosed by a protective layer of granulosa cells to form primordial follicles that will grow, mature, and eventually release the oo...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Fu, Anqi, Oberholtzer, Sydney M., Bagheri-Fam, Stefan, Rastetter, Raphael H., Holdreith, Claire, Caceres, Valeria L., John, Steven V., Shaw, Sarah A., Krentz, Kathleen J., Zhang, Xiaoyun, Hui, Chi-chung, Wilhelm, Dagmar, Jorgensen, Joan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071956/
https://ncbi.nlm.nih.gov/pubmed/30071018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1007488
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