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(68)Ga-Chelation and comparative evaluation of N,N′-bis-[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N′-diacetic acid (HBED-CC) conjugated NGR and RGD peptides as tumor targeted molecular imaging probes

Peptides containing RGD and NGR motifs display high affinity towards tumor vasculature molecular markers, integrin α(v)β(3) and CD13 receptors, respectively. In the present study, RGD and NGR peptides were conjugated with the novel acyclic chelator N,N′-bis-[2-hydroxy-5-(carboxyethyl)benzyl]ethylene...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Satpati, Drishty, Sharma, Rohit, Kumar, Chandan, Sarma, Haladhar Dev, Dash, Ashutosh
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071919/
https://ncbi.nlm.nih.gov/pubmed/30108785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00006e
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