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Aryl-alkyl-lysines: small molecular membrane-active antiplasmodial agents
Due to emerging resistance there is a steady need for new antimalarial drugs. Here, we report a new class of water soluble, non-toxic compounds, aryl-alkyl-lysines, with promising activity against the ring stage of Plasmodium falciparum. The optimal compound perturbed the plasma membrane potential a...
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| Publicado en: | Medchemcomm |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Royal Society of Chemistry
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6071861/ https://ncbi.nlm.nih.gov/pubmed/30108761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00589f |
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