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High throughput methods to measure the propensity of compounds to form intramolecular hydrogen bonding

Implementation of IMHB considerations in drug discovery needs robust and validated descriptors to experimentally verify the propensity of compounds to exhibit IMHBs. The first part of the paper presents an overview of the most common techniques to measure the propensity of compounds to form IMHBs. T...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Caron, Giulia, Vallaro, Maura, Ermondi, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071820/
https://ncbi.nlm.nih.gov/pubmed/30108824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00101k
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