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A Novel Method for the Development of Environmental Public Health Indicators and Benchmark Dose Estimation Using a Health-Based End Point for Chlorpyrifos

BACKGROUND: Organophosphorus (OP) compounds are the most widely used group of insecticides in the world. Risk assessments for these chemicals have focused primarily on 10% inhibition of acetylcholinesterase in the brain as the critical metric of effect. Aside from cholinergic effects resulting from...

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Udgivet i:Environ Health Perspect
Main Authors: Zurlinden, Todd J., Reisfeld, Brad
Format: Artigo
Sprog:Inglês
Udgivet: Environmental Health Perspectives 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071752/
https://ncbi.nlm.nih.gov/pubmed/29681141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP1743
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