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Dark chemical matter in public screening assays and derivation of target hypotheses
Compounds that are consistently inactive in many screening assays, so-called dark chemical matter (DCM), have recently experienced increasing attention. One of the reasons is that many DCM compounds may not be fully inert biologically, but may provide interesting leads for obtaining compounds that a...
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Publicado no: | Medchemcomm |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Royal Society of Chemistry
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6071712/ https://ncbi.nlm.nih.gov/pubmed/30108727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00426e |
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