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Epistatic Interactions in NS5A of Hepatitis C Virus Suggest Drug Resistance Mechanisms
Hepatitis C virus (HCV) causes a major health burden and can be effectively treated by direct-acting antivirals (DAAs). The non-structural protein 5A (NS5A), which plays a role in the viral genome replication, is one of the DAAs’ targets. Resistance-associated viruses (RAVs) harbouring NS5A resistan...
Guardat en:
| Publicat a: | Genes (Basel) |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6071292/ https://ncbi.nlm.nih.gov/pubmed/29986475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9070343 |
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