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Nucleobase and Nucleoside Analogues: Resistance and Re-Sensitisation at the Level of Pharmacokinetics, Pharmacodynamics and Metabolism

Antimetabolites, in particular nucleobase and nucleoside analogues, are cytotoxic drugs that, starting from the small field of paediatric oncology, in combination with other chemotherapeutics, have revolutionised clinical oncology and transformed cancer into a curable disease. However, even though c...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Tsesmetzis, Nikolaos, Paulin, Cynthia B. J., Rudd, Sean G., Herold, Nikolas
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071274/
https://ncbi.nlm.nih.gov/pubmed/30041457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10070240
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