Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery

Cortical spreading depression (CSD) in the CNS is suggested as a common mechanism contributing to headache. Despite strong evidence for CNS involvement in headache disorders, drug development for headache disorders remains focused on peripheral targets. Difficulty in delivering drugs across the bloo...

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Detalhes bibliográficos
Publicado no:eNeuro
Main Authors: Cottier, Karissa E., Galloway, Emily A., Calabrese, Elisa C., Tome, Margaret E., Liktor-Busa, Erika, Kim, John, Davis, Thomas P., Vanderah, Todd W., Largent-Milnes, Tally M.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
New Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071204/
https://ncbi.nlm.nih.gov/pubmed/30073201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0116-18.2018
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