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ERK and p38MAPK combine to improve survival in patients with BRAF mutant colorectal cancer
BACKGROUND: In colorectal cancer (CRC), BRAF mutations influence tumour progression. In mismatch repair-deficient (dMMR) tumours, BRAF mutations are associated with a good prognosis, whereas in MMR-competent tumours, they are detrimental. The differential expression of the downstream MAPK pathway me...
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| Published in: | Br J Cancer |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Nature Publishing Group UK
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6070918/ https://ncbi.nlm.nih.gov/pubmed/29988110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0174-y |
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