Mycophenolic Acid Derivatives with Immunosuppressive Activity from the Coral-Derived Fungus Penicillium bialowiezense

Mycophenolic acid (MPA) is a potent inosine-5′-monophosphate dehydrogenase (IMPDH) inhibitor for immunosuppressive chemotherapy. Most importantly, as the 2-morpholinoethyl ester prodrug of MPA, mycophenolate mofetil (MMF) is a well-known immunosuppressant used to prevent rejection in organ transplan...

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Pubblicato in:Mar Drugs
Autori principali: Zhang, Qing, Yang, Beiye, Li, Fengli, Liu, Mengting, Lin, Shuang, Wang, Jianping, Xue, Yongbo, Zhu, Hucheng, Sun, Weiguang, Hu, Zhengxi, Zhang, Yonghui
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070797/
https://ncbi.nlm.nih.gov/pubmed/29986508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16070230
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