Frequency of Mismatch Repair Protein Deficiency in a Puerto Rican Population with Colonic Adenoma and Adenocarcinoma

Background/Aim: Microsatellite instability (MSI) results from genetic alterations involving the mismatch repair (MMR) genes MLH1, PSM2, MSH2, and MSH6. MSI has been implicated in both sporadic CRC and Lynch syndrome. The aim of the study was to assess the frequency of alterations in MMR protein expr...

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Bibliografiske detaljer
Udgivet i:Cancer Genomics Proteomics
Main Authors: REVERÓN, DAYANA, LÓPEZ, CHRISTIAN, GUTIÉRREZ, SYLVIA, SAYEGH, ZENA E, ANTONIA, TERESITA, DUTIL, JULIE, MALAFA, MOKENGE, DOMENICO, COPPOLA
Format: Artigo
Sprog:Inglês
Udgivet: International Institute of Anticancer Research 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070705/
https://ncbi.nlm.nih.gov/pubmed/29976631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20084
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