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An in Vivo Mouse Model to Investigate the Effect of Local Anesthetic Nanomedicines on Axonal Conduction and Excitability

Peripheral nerve blocks (PNBs) using local anesthetic (LA) are superior to systemic analgesia for management of post-operative pain. An insufficiently short PNB duration following single-shot LA can be optimized by development of extended release formulations among which liposomes have been shown to...

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Détails bibliographiques
Publié dans:Front Neurosci
Auteurs principaux: Moldovan, Mihai, Alvarez, Susana, Rothe, Christian, Andresen, Thomas L., Urquhart, Andrew, Lange, Kai H. W., Krarup, Christian
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070635/
https://ncbi.nlm.nih.gov/pubmed/30093852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00494
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