Overexpression of OqxAB and MacAB efflux pumps contributes to eravacycline resistance and heteroresistance in clinical isolates of Klebsiella pneumoniae

This study investigated the characteristics and mechanisms of eravacycline resistance and heteroresistance in clinical Klebsiella pneumoniae isolates. A total of 393 clinical K. pneumoniae isolates were collected and subjected to eravacycline and tigecycline MIC determinations using the agar dilutio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Emerg Microbes Infect
Prif Awduron: Zheng, Jin-xin, Lin, Zhi-wei, Sun, Xiang, Lin, Wei-hong, Chen, Zhong, Wu, Yang, Qi, Guo-bin, Deng, Qi-wen, Qu, Di, Yu, Zhi-jian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070572/
https://ncbi.nlm.nih.gov/pubmed/30068997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41426-018-0141-y
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