Modeling gene-regulatory networks to describe cell fate transitions and predict master regulators

Complex organisms originate from and are maintained by the information encoded in the genome. A major challenge of systems biology is to develop algorithms that describe the dynamic regulation of genome functions from large omics datasets. Here, we describe TETRAMER, which reconstructs gene-regulato...

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Bibliografiske detaljer
Udgivet i:NPJ Syst Biol Appl
Main Authors: Cholley, Pierre-Etienne, Moehlin, Julien, Rohmer, Alexia, Zilliox, Vincent, Nicaise, Samuel, Gronemeyer, Hinrich, Mendoza-Parra, Marco Antonio
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Brief Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070484/
https://ncbi.nlm.nih.gov/pubmed/30083390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-018-0066-z
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