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Blocking ion channels induced by antifungal lipopeptide syringomycin E with amide-linked local anesthetics

The effects of the amide-linked (lidocaine (LDC), mepivacaine (MPV), prilocaine (PLC)) and ester-bound local anesthetics (benzocaine (BZC), procaine (PRC), and tetracaine (TTC)) on the pore-forming activity of the antifungal lipopeptide syringomycin E (SRE) in lipid bilayers were studied. Independen...

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Pubblicato in:Sci Rep
Autori principali: Zakharova, Anastasiia A., Efimova, Svetlana S., Schagina, Ludmila V., Malev, Valery V., Ostroumova, Olga S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070474/
https://ncbi.nlm.nih.gov/pubmed/30069037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30077-6
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