CMPK2 and BCL-G are associated with type 1 interferon–induced HIV restriction in humans

Type 1 interferons (IFN) are critical for host control of HIV and simian immunodeficiency virus. However, it is unknown which of the hundreds of interferon-stimulated genes (ISGs) restrict HIV in vivo. We sequenced RNA from cells that support HIV replication (activated CD4(+) T cells) in 19 HIV-infe...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: El-Diwany, Ramy, Soliman, Mary, Sugawara, Sho, Breitwieser, Florian, Skaist, Alyza, Coggiano, Candelaria, Sangal, Neel, Chattergoon, Michael, Bailey, Justin R., Siliciano, Robert F., Blankson, Joel N., Ray, Stuart C., Wheelan, Sarah J., Thomas, David L., Balagopal, Ashwin
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070316/
https://ncbi.nlm.nih.gov/pubmed/30083606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aat0843
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