Deciphering the targets of retroviral protease inhibitors in Plasmodium berghei

Retroviral protease inhibitors (RPIs) such as lopinavir (LP) and saquinavir (SQ) are active against Plasmodium parasites. However, the exact molecular target(s) for these RPIs in the Plasmodium parasites remains poorly understood. We hypothesised that LP and SQ suppress parasite growth through inhib...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Onchieku, Noah Machuki, Mogire, Reagan, Ndung'u, Loise, Mwitari, Peter, Kimani, Francis, Matoke-Muhia, Damaris, Kiboi, Daniel, Magoma, Gabriel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070271/
https://ncbi.nlm.nih.gov/pubmed/30067811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0201556
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