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Isoflurane but Not Halothane Prevents and Reverses Helpless Behavior: A Role for EEG Burst Suppression?

BACKGROUND: The volatile anesthetic isoflurane may exert a rapid and long-lasting antidepressant effect in patients with medication-resistant depression. The mechanism underlying the putative therapeutic actions of the anesthetic have been attributed to its ability to elicit cortical burst suppressi...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Brown, P Leon, Zanos, Panos, Wang, Leiming, Elmer, Greg I, Gould, Todd D, Shepard, Paul D
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070045/
https://ncbi.nlm.nih.gov/pubmed/29554264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyy029
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