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Evaluation of the efficacy of rezafungin, a novel echinocandin, in the treatment of disseminated Candida auris infection using an immunocompromised mouse model

BACKGROUND: Multiple cases of Candida auris infection have been reported with high mortality rates owing to its MDR nature. Rezafungin (previously CD101) is a novel echinocandin with enhanced stability and pharmacokinetics that achieves high plasma drug exposure and allows for once weekly dose admin...

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Pubblicato in:J Antimicrob Chemother
Autori principali: Hager, Christopher L, Larkin, Emily L, Long, Lisa A, Ghannoum, Mahmoud A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070025/
https://ncbi.nlm.nih.gov/pubmed/29897469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky153
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