Dual roles for Ikaros in regulation of macrophage chromatin state and inflammatory gene expression

Macrophage activation by bacterial lipopolysaccharide (LPS) leads to induction of a complex inflammatory gene program dependent on numerous transcription factor families. The transcription factor Ikaros has been shown to play a critical role in lymphoid cell development and differentiation, however...

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Veröffentlicht in:J Immunol
Hauptverfasser: Oh, Kyu-Seon, Gottschalk, Rachel A., Lounsbury, Nicolas W., Sun, Jing, Dorrington, Michael G., Baek, Songjoon, Sun, Guangping, Wang, Ze, Krauss, Kathleen S., Milner, Joshua D., Dutta, Bhaskar, Hager, Gordon L., Sung, Myong-Hee, Fraser, Iain D.C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069956/
https://ncbi.nlm.nih.gov/pubmed/29898962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800158
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