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Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study

BACKGROUND: Human genetic factors are important determinants of malaria risk. We investigated associations between multiple candidate polymorphisms—many related to the structure or function of red blood cells—and risk for severe Plasmodium falciparum malaria and its specific phenotypes, including ce...

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Veröffentlicht in:Lancet Haematol
Hauptverfasser: Ndila, Carolyne M, Uyoga, Sophie, Macharia, Alexander W, Nyutu, Gideon, Peshu, Norbert, Ojal, John, Shebe, Mohammed, Awuondo, Kennedy O, Mturi, Neema, Tsofa, Benjamin, Sepúlveda, Nuno, Clark, Taane G, Band, Gavin, Clarke, Geraldine, Rowlands, Kate, Hubbart, Christina, Jeffreys, Anna, Kariuki, Silvia, Marsh, Kevin, Mackinnon, Margaret, Maitland, Kathryn, Kwiatkowski, Dominic P, Rockett, Kirk A, Williams, Thomas N
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Ltd 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069675/
https://ncbi.nlm.nih.gov/pubmed/30033078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2352-3026(18)30107-8
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