Ulk1 Governs Nerve Growth Factor/TrkA Signaling by Mediating Rab5 GTPase Activation in Porcine Hemagglutinating Encephalomyelitis Virus-Induced Neurodegenerative Disorders

Porcine hemagglutinating encephalomyelitis virus (PHEV) is a highly neurovirulent coronavirus and causes neurological dysfunction in the central nervous system (CNS), but the neuropathological mechanism of PHEV remains poorly understood. We report that Unc51-like kinase 1 (Ulk1/Unc51.1) is a pivotal...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Li, Zi, Zhao, Kui, Lv, Xiaoling, Lan, Yungang, Hu, Shiyu, Shi, Junchao, Guan, Jiyu, Yang, Yawen, Lu, Huijun, He, Hongbin, Gao, Feng, He, Wenqi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Cellular Response to Infection
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069187/
https://ncbi.nlm.nih.gov/pubmed/29875237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00325-18
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