Genotoxic stress induces Sca‐1‐expressing metastatic mammary cancer cells

We describe a cell damage‐induced phenotype in mammary carcinoma cells involving acquisition of enhanced migratory and metastatic properties. Induction of this state by radiation required increased activity of the Ptgs2 gene product cyclooxygenase 2 (Cox2), secretion of its bioactive lipid product p...

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Vydáno v:Mol Oncol
Hlavní autoři: Gong, Jianlin, Lang, Benjamin J., Weng, Desheng, Eguchi, Takanori, Murshid, Ayesha, Borges, Thiago J., Doshi, Sachin, Song, Baizheng, Stevenson, Mary A., Calderwood, Stuart K.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068352/
https://ncbi.nlm.nih.gov/pubmed/29738110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12321
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