In Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL)

An in silico drug discovery pipeline for the virtual screening of plant-origin natural products (NPs) was developed to explore new direct inhibitors of TNF and its close relative receptor activator of nuclear factor kappa-B ligand (RANKL), both representing attractive therapeutic targets for many ch...

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Publicat a:Front Pharmacol
Autors principals: Melagraki, Georgia, Ntougkos, Evangelos, Papadopoulou, Dimitra, Rinotas, Vagelis, Leonis, Georgios, Douni, Eleni, Afantitis, Antreas, Kollias, George
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068282/
https://ncbi.nlm.nih.gov/pubmed/30090063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00800
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