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The role of hypoxia‐inducible factors in carotid body (patho) physiology

Hypoxia‐inducible factors mediate adaptive responses to reduced O(2) availability. In patients with obstructive sleep apnoea, repeated episodes of hypoxaemia and reoxygenation (intermittent hypoxia) are sensed by the carotid body (CB). The ensuing CB chemosensory reflex activates the sympathetic ner...

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Detalhes bibliográficos
Publicado no:J Physiol
Main Authors: Semenza, Gregg L., Prabhakar, Nanduri R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068252/
https://ncbi.nlm.nih.gov/pubmed/29359806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP275696
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