Relationships between tumour response and primary tumour location, and predictors of long-term survival, in patients with RAS wild-type metastatic colorectal cancer receiving first-line panitumumab therapy: retrospective analyses of the PRIME and PEAK clinical trials

BACKGROUND: Data from two trials of panitumumab in metastatic colorectal cancer (mCRC) were retrospectively analysed to investigate the effects of primary tumour location on early-tumour shrinkage (ETS) and depth of response (DpR), and identify factors predicting long-term survival. METHODS: Patient...

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Published in:Br J Cancer
Main Authors: Peeters, Marc, Price, Timothy, Taieb, Julien, Geissler, Michael, Rivera, Fernando, Canon, Jean-Luc, Pentheroudakis, George, Koukakis, Reija, Burdon, Peter, Siena, Salvatore
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068172/
https://ncbi.nlm.nih.gov/pubmed/30013091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-018-0165-z
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