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Improvement of antibody affinity by introduction of basic amino acid residues into the framework region
Antibodies are widely used not only as therapeutic agents but also as research tools and diagnostic agents, and extensive efforts have been made to generate antibodies that have higher affinity. It was recently reported that introduction of charged residues into the framework region of an antibody i...
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| Published in: | Biochem Biophys Rep |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Elsevier
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6068084/ https://ncbi.nlm.nih.gov/pubmed/30073208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.07.005 |
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