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Presynaptic effects of NMDA receptors enhance parvalbumin cell-mediated inhibition of pyramidal cells in mouse prefrontal cortex

BACKGROUND: Testing hypotheses regarding the role of N-methyl-D-aspartate receptor (NMDAR) hypofunction in schizophrenia requires understanding the mechanisms of NMDAR regulation of prefrontal cortex (PFC) circuit function. NMDAR antagonists are thought to produce pyramidal cell (PC) disinhibition....

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Foilsithe in:Biol Psychiatry
Main Authors: Pafundo, Diego E., Miyamae, Takeaki, Lewis, David A., Burgos, Guillermo Gonzalez
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6068001/
https://ncbi.nlm.nih.gov/pubmed/29523414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2018.01.018
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