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Carbon chain shape selectivity by the mouse olfactory receptor OR-I7

The rodent OR-I7 is an olfactory receptor exemplar activated by aliphatic aldehydes such as octanal. Normal alkanals shorter than heptanal bind OR-I7 without activating it and hence function as antagonists in vitro. We report a series of aldehydes designed to probe the structural requirements for al...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Liu, Min Ting, Ho, Jianghai, Liu, Jason, Purakait, Radhanath, Morzan, Uriel N., Ahmed, Lucky, Batista, Victor S., Matsunami, Hiroaki, Ryan, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067823/
https://ncbi.nlm.nih.gov/pubmed/29569669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C8OB00205C
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