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Apolipoprotein(a) is the Product of a Pseudogene: Implications for the Pathophysiology of Lipoprotein(a)

Apolipoprotein(a) [apo(a)] is an apolipoprotein unique to lipoprotein(a) [Lp(a)]. Although it has no known function, Lp(a) is a risk factor for accelerated atherothrombosis. We hypothesize that LPA, the gene which encodes apo(a), is a heretofore unrecognized unprocessed pseudogene created by duplica...

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Detalhes bibliográficos
Publicado no:Cureus
Main Authors: Sloop, Gregory D, Pop, Gheorghe, Weidman, Joseph J, St. Cyr, John A
Formato: Artigo
Idioma:Inglês
Publicado em: Cureus 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067813/
https://ncbi.nlm.nih.gov/pubmed/30079281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.2715
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