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Serial counts of Mycobacterium tuberculosis in sputum as surrogate markers of the sterilising activity of rifampicin and pyrazinamide in treating pulmonary tuberculosis
BACKGROUND: Since the sterilising activity of new antituberculosis drugs is difficult to assess by conventional phase III studies, surrogate methods related to eventual relapse rates are required. METHODS: A suitable method is suggested by a retrospective analysis of viable counts of Mycobacterium t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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BioMed Central
2001
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC60677/ https://ncbi.nlm.nih.gov/pubmed/11737875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-1-2 |
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