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Homogeneity of Aerosol Deposition and Mucociliary Clearance are Improved Following Ivacaftor Treatment in Cystic Fibrosis

Background: Using planar gamma scintigraphy of inhaled radioaerosols, we have developed new analytical methods for assessing homogeneity of aerosol deposition and time-dependent particle clearance on a pixel-by-pixel basis, and applied them to a therapeutic cystic fibrosis (CF) study. Methods: At ba...

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Detalhes bibliográficos
Publicado no:J Aerosol Med Pulm Drug Deliv
Main Authors: Bennett, William D., Zeman, Kirby L., Laube, Beth L., Wu, Jihong, Sharpless, Gail, Mogayzel, Peter J., Donaldson, Scott H.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067688/
https://ncbi.nlm.nih.gov/pubmed/29035122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jamp.2017.1388
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