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Folic acid-conjugated mesoporous silica nanoparticles for enhanced therapeutic efficacy of topotecan in retina cancers

In this study, topotecan-loaded mesoporous silica nanoparticles were prepared and surface conjugated with folic acid (FTMN) to enhance the therapeutic efficacy of topotecan for the treatment of retinoblastoma (RB) cancers. The particles were nano-sized and exhibited a sustained release of drug in th...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Qu, Wei, Meng, Bo, Yu, Yangyang, Wang, Shaowei
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067616/
https://ncbi.nlm.nih.gov/pubmed/30100721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S142668
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