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Is Magnetic Resonance Imaging Detection of Kidney Iron Deposition Increased in Haptoglobin 2-2 Genotype Carriers with Type 1 Diabetes?
Haptoglobin's (Hp) main role is to bind free hemoglobin (Hb), reducing its oxidative potential. The Hp–Hb complex formed is cleared from the circulation by macrophage receptor CD163. In diabetes, impaired Hp 2-2–Hb CD163 clearance and abnormal glomerular permeability allow the large Hp 2-2–Hb c...
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| Publicado no: | Antioxid Redox Signal |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6067098/ https://ncbi.nlm.nih.gov/pubmed/29298491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2017.7444 |
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