Suppression of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel Function in Thalamocortical Neurons Prevents Genetically Determined and Pharmacologically Induced Absence Seizures

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels and the I(h) current they generate contribute to the pathophysiological mechanisms of absence seizures (ASs), but their precise role in neocortical and thalamic neuronal populations, the main components of the network underlying AS g...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: David, François, Çarçak, Nihan, Furdan, Szabina, Onat, Filiz, Gould, Timothy, Mészáros, Ádám, Di Giovanni, Giuseppe, Hernández, Vivian M., Chan, C. Savio, Lőrincz, Magor L., Crunelli, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6067077/
https://ncbi.nlm.nih.gov/pubmed/29925625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0896-17.2018
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