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Structure and activity of the internal ribosome entry site within the human p27(Kip1) 5′-untranslated region
The cyclin dependent kinase inhibitor p27(Kip1) is a key cell cycle regulatory protein that is often downregulated in cancer cells. The cellular levels of p27(Kip1) are regulated, in part, through translational control mechanisms. The 5′-UTR of the p27(Kip1) mRNA is known to harbor an IRES that may...
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| Publicado no: | RNA Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6067003/ https://ncbi.nlm.nih.gov/pubmed/19106631 |
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