DICER1: A Key Player in Rheumatoid Arthritis, at the Crossroads of Cellular Stress, Innate Immunity, and Chronic Inflammation in Aging

Loss-of-function or knockout mouse models have established a fundamental role for the RNAse III enzyme DICER1 in development and tissue morphogenesis and/or homeostasis. These functions are currently assumed to result mainly from the DICER1-dependent biogenesis of microRNAs which exhibit important g...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: De Cauwer, Aurore, Mariotte, Alexandre, Sibilia, Jean, Bahram, Seiamak, Georgel, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066587/
https://ncbi.nlm.nih.gov/pubmed/30087677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01647
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