Mycobacterium Growth Inhibition Assay of Human Alveolar Macrophages as a Correlate of Immune Protection Following Mycobacterium bovis Bacille Calmette–Guérin Vaccination

BACKGROUND: In order to eliminate tuberculosis (TB), an effective vaccine is urgently needed to prevent infection with Mycobacterium tuberculosis. A key obstacle for the development of novel TB vaccines is the lack of surrogate markers for immune protection against M. tuberculosis. METHODS: We inves...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Radloff, Juliane, Heyckendorf, Jan, van der Merwe, Lize, Sanchez Carballo, Patricia, Reiling, Norbert, Richter, Elvira, Lange, Christoph, Kalsdorf, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066571/
https://ncbi.nlm.nih.gov/pubmed/30087678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01708
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