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CRISPR/Cas9-Based Editing of Streptomyces for Discovery, Characterization, and Production of Natural Products

Microbial natural products (NPs) especially of the Streptomyces genus have been regarded as an unparalleled resource for pharmaceutical drugs discovery. Moreover, recent progress in sequencing technologies and computational resources further reinforces to identify numerous NP biosynthetic gene clust...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Tao, Weixin, Yang, Anna, Deng, Zixin, Sun, Yuhui
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6066502/
https://ncbi.nlm.nih.gov/pubmed/30087666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01660
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